Pfam 33.1 (May 2024,
18259 entries)
The Pfam database is a large collection of protein
families, each represented by multiple sequence alignments
and hidden Markov models (HMMs).
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Proteins are generally composed of one or more functional regions,
commonly termed domains. Different combinations of domains give
rise to the diverse range of proteins found in nature. The identification
of domains that occur within proteins can therefore provide insights
into their function.
Pfam also generates higher-level groupings of related entries, known as
clans. A clan is a collection of Pfam entries which are
related by similarity of sequence, structure or profile-HMM.
The data presented for each entry is based on the
极速加速器安卓官网jisu99
but information on individual UniProtKB sequences can still be found by entering the protein accession.
Pfam full alignments are available from searching a variety of databases, either to provide
different accessions (e.g. all UniProt and NCBI GI) or different levels of redundancy.
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萤火虫加速器电脑版下载-快连加速器app
- Analyze your protein sequence for Pfam matches
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- Look at the domain organisation of a protein sequence
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more information
萤火虫加速器电脑版下载-快连加速器app
Paste your protein sequence here to find matching Pfam entries.
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This search will use and an E-value of 1.0. You can set your own search
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Enter a entry identifier (e.g. Piwi) or accession
(e.g. PF02171) to see all data for that entry.
萤火虫加速器电脑版下载-快连加速器app
Enter a clan identifier (e.g. Kazal) or accession
(e.g. CL0005) to see information about that clan.
萤火虫加速器电脑版下载-快连加速器app
Enter a sequence identifier (e.g. VAV_HUMAN) or accession
(e.g. P15498).
萤火虫加速器电脑版下载-快连加速器app
Enter the PDB identifier (e.g. 2abl) for the structure in the
Protein DataBank.
萤火虫加速器电脑版下载-快连加速器app
Search for keywords in text data in the Pfam database.
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萤火虫加速器电脑版下载-快连加速器app
If you find Pfam useful, please consider
极速加速器安卓官网 the reference
that describes this work:
The Pfam protein families database in 2024:
S. El-Gebali, J. Mistry, A. Bateman, S.R. Eddy, A. Luciani,
S.C. Potter, M. Qureshi, L.J. Richardson, G.A. Salazar, A. Smart,
E.L.L. Sonnhammer, L. Hirsh, L. Paladin, D. Piovesan, S.C.E. Tosatto,
R.D. Finn
Nucleic Acids Research (2024)
doi: 10.1093/nar/gky995
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